There are two main tasks involved in flux balance analysis: developing a model, and then solving it. Pathway Tools can aid in both of these tasks. Developing an accurate FBA model might require the addition of new reactions to a PGDB, altering the directionality of some reactions, modifying the biomass reaction (which lists all the chemical components of the cellular biomass), and adding new nutrients and secretions. The Pathway Tools FBA module can guide the user by suggesting changes, such as possible new reactions to add to produce a needed compound.
We are pleased to announce that SRI will be hosting a tutorial on the new Pathway Tools module for generating and refining metabolic flux models using flux-balance analysis at SRI's main campus in Menlo Park, CA from June 21-22. The purpose of the workshop is to describe the use of this new module in significant detail, to offer advice on strategies for refining FBA models, and to assist attendees in hands-on refinement of Pathway Tools based FBA models.
More details and registration are available at http://ptools-fba.eventbrite.com/ A remote online attendance option for the tutorial is available.
More details and registration are available at http://ptools-fba.eventbrite.com/ A remote online attendance option for the tutorial is available.
If you're at all interested in these new capabilities, please join us -- we'd love to see you!